Quartet

Potential Benefits of Quadripolar Technology

• Shorter implant times and decreased fluoroscopic exposure^1,5
• Fewer surgical revisions²
• More basal pacing opportunities (pacing basally has been shown to be associated with improved outcomes)^6,7

Overall, quadripolar technology can lead to greater CRT implant and postoperative efficiencies while providing improved CRT efficacy.

MRI Readiness

The Quartet quadripolar LV lead, when combined with approved devices, allows full-body, 1.5T and 3T MRI scans that meet certain scan conditions.*

• Meets industry-standard MRI testing requirements
• Capable of full body 1.5T and 3T MRI imaging scans

*See MRI Ready Systems Manual for device and lead combinations and associated MRI scan parameters. Quartet quadripolar LV Lead is MR Conditional in the 86cm lead length.
 

References
 

1. Sperzel, J., Dänschel, W., Gutleben, K. J., Kranig, W., Mortensen, P., Connelly, D., … Rinaldi, C. A. (2012). First prospective, multi-centre clinical experience with a novel left ventricular quadripolar lead. Europace, 14(3), 365-372
2. Forleo, G. B., Della Rocca, D. G., Papavasileiou, L. P., Molfetta, A. D., Santini, L., & Romeo, F. (2011). Left ventricular pacing with a new quadripolar transvenous lead for CRT: Early results of a prospective comparison with conventional implant outcomes. Heart Rhythm, 8(1), 31-37. https://dx.doi.org/10.1016/j.hrthm.2010.09.076
3. Data compiled from clinical study results, on file in Report 60034670.
4. Thibault, B., Dubuc, M., Guerra, P. G., Karst, E., Ryu, K., Paiement, P., … Farazi, T. (2011). Electrode selection to avoid phrenic stimulation with a quadripolar left heart lead. Heart Rhythm, 8(5), S68. https://dx.doi.org/10.1016/j.hrthm.2011.03.023
5. Duray, G. Z., Hohnloser, S. H., & Israel, C. W. (2008). Coronary sinus side branches for cardiac resynchronization therapy: Prospective evaluation of availability, implant success, and procedural determinants. Journal of Cardiovascular Electrophysiology, 19(5), 489-494. https://dx.doi.org/10.1111/j.1540-8167.2007.01096.x
6. Singh, J. P., Klein, H. U., Huang, D. T., Reek, S., Kuniaa, M. Quesada, A., … Moss, A. J. (2011). Left ventricular lead position and clinical outcome in the Multicenter Automatic Defibrillator Implantation Trial Cardiac Resynchronization Therapy (MADIT-CRT) trial. Circulation, 123(11), 1159-1166. https://dx.doi.org/10.1161/CIRCULATIONAHA.110.000646
7. Merchant, F. M., Heist, E. K., McCarty, D., Kumar, P., Das, S., Blendea, D., … Singh, J. P. (2010). Impact of segmental left ventricle lead position on cardiac resynchronization therapy outcomes. Heart Rhythm, 7(5), 639-644. https://dx.doi.org/10.1016/j.hrthm.2010.01.035
8. Jenney, C., Tan, J., Karicherla, A., Burke, J., & Helland, J. (2005). A new insulation material for cardiac leads with potential for improved performance. Heart Rhythm, 2(5), S318-319. https://dx.doi.org/10.1016/j.hrthm.2005.02.1004