For patients with advanced heart failure, the likelihood of long-term survival without an LVAD or a heart transplant is extremely low.
Due to poor outcomes associated with long-term inotrope use when a transplant or LVAD is an option, the American Heart Association (AHA), American College of Cardiology (ACC), and Heart Failure Society of America (HFSA) have issued a 3 Harm recommendation. This indicates that the risks of long-term inotrope therapy far outweigh the benefits if a transplant or LVAD if available.2
The joint committees of the AHA recently evaluated the data on LVAD patient outcomes and granted a 1A Recommendation for heart failure patients who are dependent on intravenous inotropes or cannot be weaned from temporary mechanical circulatory support (MCS).
“Recommendations for mechanical circulatory support referenced studies that support the recommendations are summarized in the Online Data Supplements”
1A Recommendation is the strongest Class of Recommendation (COR) and the highest level of evidence (LOE). This means that benefits are supported by strong data and far outweigh the risks.
Repetitive hospitalizations for heart failure (2 or more events in a year)
Staircase diuretic requirements over time to maintain clinical stability (e.g., an increase of oral loop diuretics therapy by 50% in the preceding 6 months)
Intolerance to neurohormonal therapy with onset of cardio-renal perturbation
Left Ventricular Assist Devices: A primer for the general cardiologist
The HeartMate 3™ LVAD has significantly advanced the field of LVAD therapy, setting the standard with innovation and exceptional clinical outcomes. Its Full MagLev™ Flow Technology ensures gentle blood handling, minimizing complications and reducing hemocompatibility-related adverse events (HRAEs).**
** Key adverse events include pump thrombosis, stroke and gastrointestinal (GI) bleeding.
For more information about the HeartMate 3 LVAD, see the clinical evidence or ask a clinical specialist.
Left Ventricular Assist Devices at the Crossroad of Innovation in Advanced Heart Failure: Journal of Cardiac Failure
Clinics are listed in order of geographic proximity from the information entered in the locator. Abbott does not endorse any of the clinics on this locator, but merely provides them as a courtesy to patients. Nor does Abbott represent that this is a full list of clinics in a particular location. Though Abbott attempts to regularly update the locator, the locator may not have the latest information regarding the clinic or provider, or availability of product. The clinics are included in the locator because they are certified as a HeartMate LVAD implanting center, have ordered at least one HeartMate LVAD in the last 12 months, and have all HeartMate LVAD device-related equipment required for patient management. The number of orders has been validated; the number of implants has not been validated. This locator includes US clinics only. No clinics or healthcare professionals (HCPs) have paid or received a fee to be listed, but some HCPs within the clinics on this locator may purchase products from Abbott, provide consulting services to Abbott, and/or may have a financial relationship with Abbott. The locator is not meant to be an endorsement for any particular clinic, nor does it represent the qualifications of the HCPs at the clinic. Note that Abbott is a medical device manufacturer and cannot provide medical advice.
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A resource to help patients learn more about heart failure and understand how LVAD therapy can save their life.
*Patients on inotropes who did not receive a transplant or left ventricular assist device.
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